Spiriva/Spiriva Respimat

Spiriva/Spiriva Respimat

tiotropium bromide

Manufacturer:

Boehringer Ingelheim

Distributor:

Metro Drug
Concise Prescribing Info
Contents
Tiotropium Br
Indications/Uses
Maintenance treatment of patients w/ COPD (including chronic bronchitis & emphysema); associated dyspnoea, the improvement of COPD compromised quality of life & reduction of exacerbations. Spiriva Respimat As add-on maintenance treatment for the improvement of asthma symptoms, quality of life & reduction of exacerbations in patients ≥6 yr w/ asthma who remain symptomatic on at least inhaled corticosteroids.
Dosage/Direction for Use
Spiriva 1 cap inhaled once daily via Handihaler (1 puff once daily at the same time of day). Spiriva Respimat 2 puff once daily at the same time of day.
Contraindications
Hypersensitivity to atropine or its derivatives (eg, ipratropium or oxitropium).
Special Precautions
Immediate hypersensitivity reactions may occur. Not for initial treatment of acute episodes of bronchospasm or for relief of acute symptoms. Patients w/ narrow-angle glaucoma, prostatic hyperplasia or bladder-neck obstruction. May cause inhalation-induced bronchospasm. Not to be used more frequently than once daily. Occurrence of dizziness or blurred vision may influence the ability to drive & use machinery. Moderate to severe renal impairment (CrCl ≤50 mL/min). Avoid use during pregnancy. Lactation. Spiriva Avoid the powd to enter from entering the eyes. Contains lactose monohydrate. Infants & childn. Spiriva Respimat Not to be used as 1st-line treatment of asthma; use more frequently than once daily. Avoid the soln or mist from entering the eyes. Contains benzalkonium Cl which may cause wheezing & breathing difficulties especially in patients w/ asthma. Childn <1 yr w/ asthma.
Adverse Reactions
Dehydration; dizziness, insomnia; blurred vision, glaucoma, increased IOP; atrial fibrillation, supraventricular tachycardia, tachycardia, palpitations; cough, dysphonia, pharyngitis, bronchospasm, epistaxis, laryngitis, sinusitis; usually mild dry mouth, constipation, GERD, oropharyngeal candidiasis, intestinal obstruction including ileus paralytic, dysphagia, gingivitis, glossitis, stomatitis; rash, angioedema, hypersensitivity (including immediate reactions), pruritus, urticaria, dry skin, skin infection & ulcer; joint swelling; urinary retention (usually in men w/ predisposing factors), dysuria, UTI.
Drug Interactions
Not recommended w/ chronic co-administration w/ other anticholinergic drugs.
MIMS Class
Antiasthmatic & COPD Preparations
ATC Classification
R03BB04 - tiotropium bromide ; Belongs to the class of other inhalants used in the treatment of obstructive airway diseases, anticholinergics.
Presentation/Packing
Form
Spiriva inhalation powd cap 18 mcg
Packing/Price
(+ Handihaler 1's (P281)) 30's (P1,926.29/pack)
Form
Spiriva Respimat inhaler 2.5 mcg/puff
Packing/Price
(+ 4 mL cartridge) 60 puff x 1's (P2,710.78/canister)
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